Post ASH speaker abstracts 2019

DIAGNOSTICS

 

Abstracts selected by Cathy Burton (HMDS Leeds)

Whole Genome Sequencing

Abstract 1525
Whole Genome Sequencing Identifies Single Nucleotide Variants, Structural and Copy Number Abnormalities with a High Sensitivity in Hematological Neoplasm: An All in One Diagnostic Tool Tested on 3241 Cases

Abstract (PDF)

 

Abstract 3943
Using Whole Genome Sequencing (WGS) of 3256 Patients with Hematologic Malignancies to Determine Genome Instability

Abstract (PDF)

 

Lymphoid

Abstract 344
Prognostic Significance of MYC Single, Double, Triple Hit and MYC-Translocation Partner Status in Diffuse Large B-Cell Lymphoma – a Study By the Lunenburg Lymphoma Biomarker Consortium (LLBC)

Abstract (PDF)

 

Abstract 921
The Double-Hit Gene Expression Signature Defines a Clinically and Biologically Distinct Subgroup within GCB-DLBCL

Abstract (PDF)

 

CLL

Abstract 1844
The Combination of Complex Karyotypes’ Subtypes and IGHV Mutational Status Provides Prognostic and Predictive Information in Chronic Lymphocytic Leukemia

Abstract (PDF)

 

Myeloma

Abstract 112
Clinical Significance and Transcriptional Profiling of Persistent Minimal Residual Disease (MRD) in Multiple Myeloma (MM) Patients with Standard-Risk (SR) and High-Risk (HR) Cytogenetics

Abstract (PDF)

 

Abstract 4452
The Prognostic Impact of t(14;16) in Multiple Myeloma: A Multicenter Retrospective Study of 213 Patients. Is It Time to Revise the Revised ISS?

Abstract (PDF)

 

Abstract 4449
Impact of Acquired Del(17p) in Patients with Multiple Myeloma

Abstract (PDF)

 

Myeloid

Abstract 292
Molecular Predictors and Current Management of Minimal Residual Disease (MRD) Following Induction Chemotherapy for Acute Myeloid Leukemia (AML)

Abstract (PDF)

 

Abstract 1534
Comprehensive Molecular Profiling of FLT3-Mutated Acute Myeloid Leukemia (AML) Patients Treated within the Ratify Trial (Alliance C10603)

Abstract (PDF)

 

Abstract 1471
AML with Mutations in IDH1 and DNMT3A Exhibits a Distinct Epigenetic Signature with Poorer Overall Survival

Abstract (PDF)